Open Access<p>Disk-Diffusion Testing Is an Inappropriate Screening Tool for Cephalosporin-Resistant Gonorrhoea Strains in Clinical Practice in China</p>
Author(s) -
Yang Han,
Yue-Ping Yin,
Wenqi Xu,
Xiaoyu Zhu,
Shaochun Chen,
Xiu-Qin Dai,
Ligang Yang,
Bang-Yong Zhu,
Na Zhong,
Wenling Cao,
Xiaohui Zhang,
Zhao-Hui Wu,
Linhong Yuan,
Zhong-Jie Zheng,
Jun Liu,
XiangSheng Chen
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s248030
Subject(s) - cefixime , neisseria gonorrhoeae , ceftriaxone , agar dilution , medicine , cephalosporin , microbiology and biotechnology , antibiotics , minimum inhibitory concentration , biology
Injectable ceftriaxone and oral cefixime are the last agents effective against Neisseria gonorrhoeae . In vitro antimicrobial-susceptibility testing (AST) is done to identify the most efficacious antibiotic needed to combat the infection in that particular individual. The objective of this study was to evaluate whether Kirby-Bauer (KB) disk-diffusion tests can detect N. gonorrhoeae isolates that have decreased susceptibility to ceftriaxone and cefixime for appropriate clinical management.