
Determinants of Drug-Induced Hepatotoxicity Among Patients with Human Immunodeficiency Virus Taking a High Dose of Rifapentine Plus Isoniazid Drugs at the All Africa Leprosy Tuberculosis Rehabilitation and Training Center in Addis Ababa, Ethiopia
Author(s) -
Leuel Lisanwork Arage,
Haji Aman Deybasso,
Delelegn Yilma Gebremichael,
Binyam Gintamo Nuramo,
Zelalem Negash Mekuria
Publication year - 2021
Publication title -
hiv/aids
Language(s) - English
Resource type - Journals
ISSN - 1179-1373
DOI - 10.2147/hiv.s300135
Subject(s) - rifapentine , medicine , tuberculosis , leprosy , isoniazid , odds ratio , latent tuberculosis , confidence interval , immunology , mycobacterium tuberculosis , pathology
The drugs for the treatment of latent Tuberculosis are potentially hepatotoxic and can lead to drug-induced hepatotoxicity. The current study aimed at identifying the determinants of anti-tuberculosis drug-induced hepatotoxicity among patients living with Human Immunodeficiency Virus taking Isoniazid and rifapentine at All Africa Leprosy Tuberculosis Rehabilitation and Training Center in Addis Ababa, Ethiopia.