Open AccessCorosolic Acid Protects Rat Chondrocytes Against IL-1β-Induced ECM Degradation by Activating Autophagy via PI3K/AKT/mTOR Pathway and Ameliorates Rat Osteoarthritis
Author(s) -
Ho Jae Han,
Ming Chen,
Zhenyu Li,
Siqi Zhou,
Yingbin Wu,
Wei Jiang
Publication year - 2022
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s365279
Subject(s) - autophagy , pi3k/akt/mtor pathway , protein kinase b , chemistry , extracellular matrix , aggrecan , microbiology and biotechnology , western blot , osteoarthritis , signal transduction , cancer research , biochemistry , biology , medicine , pathology , apoptosis , alternative medicine , gene , articular cartilage