Open AccessNovel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights
Author(s) -
Tarfah AlWarhi,
Ahmed M. El Kerdawy,
Mohamed A. Said,
Amgad Albohy,
Zainab M. Elsayed,
Nada Aljaeed,
Eslam B. Elkaeed,
Wagdy M. Eldehna,
Hatem A. AbdelAziz,
Miral A Abdelmoaz
Publication year - 2022
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s356988
Subject(s) - erlotinib , docking (animal) , apoptosis , ic50 , chemistry , epidermal growth factor receptor , cell culture , pyrazoline , cell growth , a549 cell , cytotoxic t cell , protein data bank (rcsb pdb) , mtt assay , cancer research , pharmacology , in vitro , stereochemistry , receptor , biochemistry , biology , medicine , nursing , organic chemistry , genetics