Open AccessPharmacokinetics and Bioequivalence Evaluation of Two Montelukast Sodium Chewable Tablets in Healthy Chinese Volunteers Under Fasted and Fed Conditions
Author(s) -
Weihong Li,
Yanrong Wang,
Yingzi Pei,
Yue Xia
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s298355
Subject(s) - bioequivalence , pharmacokinetics , medicine , cmax , crossover study , area under the curve , montelukast , pharmacology , adverse effect , pharmacodynamics , placebo , asthma , alternative medicine , pathology
The aim of this study was to assess and compare the pharmacokinetic (PK) properties and bioequivalence of montelukast sodium chewable tablets prepared by two different manufacturers in healthy Chinese volunteers to obtain adequate PK evidence for the registration approval of the test formulation.