Open Access
<p>Cordycepin Alleviates Anterior Cruciate Ligament Transection (ACLT)-Induced Knee Osteoarthritis Through Regulating TGF-β Activity and Autophagy</p>
Author(s) -
Xiaomei Tao,
Pengfei Liu,
Hong-Yan Gu,
Dongbo Lian,
Lei Gao,
Tao Wen,
Dan Yan,
Bin Zhao
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s251893
Subject(s) - osteoarthritis , autophagy , anterior cruciate ligament , medicine , transforming growth factor , cartilage , endocrinology , articular cartilage damage , staining , pathology , articular cartilage , chemistry , surgery , anatomy , apoptosis , biochemistry , alternative medicine
Osteoarthritis is the most prevalent articular disease in the elderly. We aimed to explore the role of cordycepin (COR) in the progression and development of osteoarthritis and its correlation with TGF-β activity and autophagy.