Open AccessSputum <em>Moraxella catarrhalis</em> strains exhibit diversity within and between COPD subjects
Author(s) -
Lauren George,
Richard D. Haigh,
Vijay Mistry,
Koirobi Haldar,
Michael R. Barer,
Marco R. Oggioni,
Christopher E. Brightling
Publication year - 2018
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s180961
Subject(s) - medicine , moraxella catarrhalis , copd , sputum , moraxella (branhamella) catarrhalis , microbiology and biotechnology , moraxella , immunology , streptococcus pneumoniae , bacteria , pathology , biology , antibiotics , tuberculosis , genetics
Moraxella catarrhalis is implicated in the pathogenesis of some COPD exacerbations. We sought to investigate whether the M. catarrhalis strain is variable between COPD subjects; that an exacerbation is associated with acquisition of a new strain and that certain strains are more commonly associated with exacerbations.