Open AccessLncRNA NOP14-AS1 Promotes Tongue Squamous Cell Carcinoma Progression by Targeting MicroRNA-665/HMGB3 Axis
Author(s) -
Jiayi Li,
Sanhong Fan,
Shuang Liu,
Guang Yang,
Qingsong Jin,
Xiao Zhang
Publication year - 2021
Publication title -
cancer management and research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s293322
Subject(s) - gene knockdown , microrna , antisense rna , cancer research , cell culture , biology , cell , cell growth , downregulation and upregulation , apoptosis , flow cytometry , oncogene , microbiology and biotechnology , rna , gene , cell cycle , biochemistry , genetics
The expression profile, clinical effects, and detailed roles of NOP14 antisense RNA 1 (NOP14-AS1) in tongue squamous cell carcinoma (TSCC) remain ambiguous and need to be further explored. Thus, this work was initiated to offer further solid evidence regarding the expression and roles of NOP14-AS1 in TSCC. Furthermore, additional efforts were exerted to reveal the molecular events by which NOP14-AS1 affects the malignant behaviours of TSCC.