Open AccessLong Non-Coding RNA LINC00466 Knockdown Inhibits Tongue Squamous Cell Carcinoma Malignancy by Targeting microRNA-493/HMGA2
Author(s) -
Chao Hou,
Yanli Dong,
Bo Du
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s282625
Subject(s) - downregulation and upregulation , gene knockdown , microrna , cell growth , cancer research , biology , cell , hmga2 , in vivo , apoptosis , cell migration , microbiology and biotechnology , gene , biochemistry , genetics
Long intergenic non-protein-coding RNA 00466 ( LINC00466 ) promotes lung adenocarcinoma progression. Nonetheless, the expression and precise roles of LINC00466 in tongue squamous cell carcinoma (TSCC) remains uncertain and warrant further investigation. Hence, the present study aimed to examine the LINC00466 effects on the aggressive TSCC cell characteristics and to elucidate the potential underlying mechanisms.