Open AccessEffects of LncRNA HCP5/miR-214-3p/MAPK1 Molecular Network on Renal Cell Carcinoma Cells
Author(s) -
Junfeng Hao,
Pei Chen,
Heyi Li,
Yajing Li,
Yuling Zhang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s274426
Subject(s) - metastasis , cancer research , clear cell renal cell carcinoma , renal cell carcinoma , cell growth , biology , cell , western blot , oncology , medicine , cancer , gene , genetics
Recent researches have shown that long non-coding RNA (LncRNA) is often disordered and acts in many carcinomas. Clear cell renal cell carcinoma (ccRCC) is the main reason for carcinoma-related deaths, which are mainly caused by the metastasis. HCP5 is a newly discovered LcnRNA. Early studies have found that HCP5 acts in neoplasm metastasis, but the mechanism of HCP5 in ccRCC is still unclear.