Open Access<p>Oncolytic Vaccinia Virus-Mediated Antitumor Effect and Cell Proliferation Were Promoted in PTC by Regulating circRNA_103598/miR-23a-3p/IL-6 Axis</p>
Author(s) -
Shuilong Zhang,
Qiang Wang,
Dewei Li,
Bo Huang,
Xia Hou,
Dongliang Wang,
Zhifu Xiao,
Hongjing Meng,
Yuhang Zhang,
Lingxiang Dong
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s273072
Subject(s) - oncolytic virus , gene knockdown , cancer research , cell growth , chemistry , cell culture , mtt assay , luciferase , microrna , microbiology and biotechnology , biology , transfection , gene , biochemistry , tumor cells , genetics
Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy, and cases have been rising steadily worldwide in the past few decades. Despite great progress having been made in surgery and chemotherapy for PTC, the survival rate of PTC patients has not increased significantly. Therefore, there is an urgent need to explore novel treatment strategies.