SHP-2 Interacts with CD81 and Regulates the Malignant Evolution of Colorectal Cancer by Inhibiting Epithelial–Mesenchymal Transition | Zendy

Huaqin Yuan | Zendy; Jun Zhao | Zendy; Yang Yang | Zendy; Rongfu Wei | Zendy; Zhu Liang-xue | Zendy; Jie Wang | Zendy; Meiqing Ding | Zendy; Mingyun Wang | Zendy; Yanhong Gu | Zendy

Open Access

SHP-2 Interacts with CD81 and Regulates the Malignant Evolution of Colorectal Cancer by Inhibiting Epithelial–Mesenchymal Transition

Author(s) -

Huaqin Yuan,

Jun Zhao,

Yang Yang,

Rongfu Wei,

Zhu Liang-xue,

Jie Wang,

Meiqing Ding,

Mingyun Wang,

Yanhong Gu

Publication year - 2020

Publication title -

cancer management and research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.024

H-Index - 40

ISSN - 1179-1322

DOI - 10.2147/cmar.s270813

Subject(s) - colorectal cancer , cancer research , cancer , epithelial–mesenchymal transition , metastasis , apoptosis , cell growth , cancer cell , chemistry , biology , medicine , biochemistry

Colon cancer is a common malignant tumor of the digestive system. This project verified the negative role of protein tyrosine phosphatase (SHP-2) in the regulation of colon cancer and further clarified the key targets and molecular mechanisms in the regulation process.

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