Open Access<p>Long Noncoding RNA KCNMB2-AS1 Increases ROCK1 Expression by Sponging microRNA-374a-3p to Facilitate the Progression of Non–Small-Cell Lung Cancer</p>
Author(s) -
Yang Huang,
Ziyi Wang,
Zhenyuan Wang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s270646
Subject(s) - rock1 , cancer research , gene silencing , gene knockdown , microrna , competing endogenous rna , biology , tumor progression , flow cytometry , cell growth , long non coding rna , antisense rna , apoptosis , microbiology and biotechnology , rna , cancer , kinase , gene , protein kinase a , biochemistry , genetics
The expression and roles of most long noncoding RNAs (lncRNAs) in non-small-cell lung cancer (NSCLC) remain poorly understood. Thus, this study investigated KCNMB2 antisense RNA 1 (KCNMB2-AS1) expression in NSCLC and determined the roles and mechanisms of KCNMB2-AS1 in regulating NSCLC progression.