Long Noncoding RNA LINC00839 Promotes the Malignant Progression of Osteosarcoma by Competitively Binding to MicroRNA-454-3p and Consequently Increasing c-Met Expression | Zendy

Yang Zhang | Zendy; Hai Guo | Zendy; Li Ma | Zendy; Xiaoyong Chen | Zendy; Guangdong Chen | Zendy

Open Access

<p>Long Noncoding RNA LINC00839 Promotes the Malignant Progression of Osteosarcoma by Competitively Binding to MicroRNA-454-3p and Consequently Increasing c-Met Expression</p>

Author(s) -

Yang Zhang,

Hai Guo,

Li Ma,

Xiaoyong Chen,

Guangdong Chen

Publication year - 2020

Publication title -

cancer management and research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.024

H-Index - 40

ISSN - 1179-1322

DOI - 10.2147/cmar.s269774

Subject(s) - microrna , long non coding rna , non coding rna , osteosarcoma , cancer research , biology , microbiology and biotechnology , rna , medicine , gene , genetics

This study was conducted to determine the expression and prognostic relevance of long intergenic non-protein coding RNA 839 (LINC00839) in osteosarcoma (OS) and to explore the detailed roles of LINC00839 in regulating OS cell activities and the mechanisms responsible for its cancer-promoting activity in OS.

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