Open Access<p>Long Noncoding RNA LINC00839 Promotes the Malignant Progression of Osteosarcoma by Competitively Binding to MicroRNA-454-3p and Consequently Increasing c-Met Expression</p>
Author(s) -
Zhilin Yang,
Hai Guo,
Li Ma,
Xiaoyong Chen,
Guangdong Chen
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s269774
Subject(s) - microrna , long non coding rna , non coding rna , osteosarcoma , cancer research , biology , microbiology and biotechnology , rna , medicine , gene , genetics
This study was conducted to determine the expression and prognostic relevance of long intergenic non-protein coding RNA 839 (LINC00839) in osteosarcoma (OS) and to explore the detailed roles of LINC00839 in regulating OS cell activities and the mechanisms responsible for its cancer-promoting activity in OS.