Exosome-Encapsulated MicroRNA-21 from Esophageal Squamous Cell Carcinoma Cells Enhances Angiogenesis of Human Umbilical Venous Endothelial Cells by Targeting SPRY1 | Zendy

Huirong Zhuang | Zendy; Hongjun Wang | Zendy; Haibo Yang | Zendy; Hongli Li | Zendy

Open Access

<p>Exosome-Encapsulated MicroRNA-21 from Esophageal Squamous Cell Carcinoma Cells Enhances Angiogenesis of Human Umbilical Venous Endothelial Cells by Targeting SPRY1</p>

Author(s) -

Huirong Zhuang,

Hongjun Wang,

Haibo Yang,

Hongli Li

Publication year - 2020

Publication title -

cancer management and research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.024

H-Index - 40

ISSN - 1179-1322

DOI - 10.2147/cmar.s259077

Subject(s) - angiogenesis , downregulation and upregulation , cancer research , microvesicles , exosome , microrna , cell growth , metastasis , medicine , biology , microbiology and biotechnology , cancer , biochemistry , genetics , gene

Esophageal squamous cell carcinoma (ESCC) persists among the most prevalent cancers worldwide. Angiogenesis represents a crucial element necessitated for tumor growth and metastasis in ESCC. In this study, we aimed to study the effect of microRNA (miR)-21 on angiogenesis in ESCC and its underlying mechanism.

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