Open Access<p>Exosome-Encapsulated MicroRNA-21 from Esophageal Squamous Cell Carcinoma Cells Enhances Angiogenesis of Human Umbilical Venous Endothelial Cells by Targeting SPRY1</p>
Author(s) -
Huirong Zhuang,
Hongjun Wang,
Haibo Yang,
Hongli Liu
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s259077
Subject(s) - angiogenesis , downregulation and upregulation , cancer research , microvesicles , exosome , microrna , cell growth , metastasis , medicine , biology , microbiology and biotechnology , cancer , biochemistry , genetics , gene
Esophageal squamous cell carcinoma (ESCC) persists among the most prevalent cancers worldwide. Angiogenesis represents a crucial element necessitated for tumor growth and metastasis in ESCC. In this study, we aimed to study the effect of microRNA (miR)-21 on angiogenesis in ESCC and its underlying mechanism.