Knockdown of CircCRIM1 Inhibits HDAC4 to Impede Osteosarcoma Proliferation, Migration, and Invasion and Facilitate Autophagy by Targeting miR-432-5p | Zendy

Jun Liu | Zendy; Guang Feng | Zendy; Zhengwei Li | Zendy; Rui Li | Zendy; Peng Xia | Zendy

Open Access

<p>Knockdown of CircCRIM1 Inhibits HDAC4 to Impede Osteosarcoma Proliferation, Migration, and Invasion and Facilitate Autophagy by Targeting miR-432-5p</p>

Author(s) -

Jun Liu,

Guang Feng,

Zhengwei Li,

Rui Li,

Peng Xia

Publication year - 2020

Publication title -

cancer management and research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.024

H-Index - 40

ISSN - 1179-1322

DOI - 10.2147/cmar.s253130

Subject(s) - gene knockdown , hdac4 , autophagy , chemistry , cell growth , microbiology and biotechnology , microrna , western blot , histone deacetylase , gene silencing , cancer research , mtt assay , biology , histone , biochemistry , gene , apoptosis

Circular RNAs (circRNAs) serve for a genre of considerable modulatory molecules that have been largely researched in human cancers. However, the contribution of circRNA cysteine-rich transmembrane bone morphogenetic protein regulator 1 (circCRIM1) to osteosarcoma (OS) is completely unclear.

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