Open Access<p>Knockdown of CircCRIM1 Inhibits HDAC4 to Impede Osteosarcoma Proliferation, Migration, and Invasion and Facilitate Autophagy by Targeting miR-432-5p</p>
Author(s) -
Jun Li,
Guang Feng,
Zhengwei Li,
Rui Li,
Peng Xia
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s253130
Subject(s) - gene knockdown , hdac4 , autophagy , chemistry , cell growth , microbiology and biotechnology , microrna , western blot , histone deacetylase , gene silencing , cancer research , mtt assay , biology , histone , biochemistry , gene , apoptosis
Circular RNAs (circRNAs) serve for a genre of considerable modulatory molecules that have been largely researched in human cancers. However, the contribution of circRNA cysteine-rich transmembrane bone morphogenetic protein regulator 1 (circCRIM1) to osteosarcoma (OS) is completely unclear.