Open Access<p>Long Noncoding RNA CCAT1 Functions as a Competing Endogenous RNA to Upregulate ITGA9 by Sponging MiR-296-3p in Melanoma</p>
Author(s) -
Jinghua Fan,
Xiaoxiao Kang,
Limin Zhao,
Yan Zheng,
Jun Yang,
Di Li
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s252635
Subject(s) - melanoma , gene knockdown , cancer research , competing endogenous rna , apoptosis , flow cytometry , cell growth , long non coding rna , downregulation and upregulation , chemistry , microbiology and biotechnology , western blot , biology , biochemistry , gene
Melanoma is aggressive and lethal melanocytic neoplasm, and its incidence has increased worldwide in recent decades. Accumulating evidence has showed that various long noncoding RNAs (lncRNAs) participated in occurrence of malignant tumors, including melanoma. The present study was designed to investigate function of lncRNA colon cancer-associated transcript-1 (CCAT1) in melanoma.