Open Access<p>Lidocaine Suppresses Cell Proliferation and Aerobic Glycolysis by Regulating circHOMER1/miR-138-5p/HEY1 Axis in Colorectal Cancer</p>
Author(s) -
Juan Du,
Liying Zhang,
Hongzhong Ma,
Yang Wang,
Pengpeng Wang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s244973
Subject(s) - chemistry , viability assay , apoptosis , cell growth , cancer research , flow cytometry , microrna , microbiology and biotechnology , biology , biochemistry , gene
Increasing evidence has uncovered the anticancer activity of lidocaine in many cancers. However, the role and the underlying molecular mechanism of lidocaine in colorectal cancer (CRC) remain poorly understood.