Open Access<p>Exercise Training Induced Changes In Nuclear Magnetic Resonance-Measured Lipid Particles In Mild Cognitively Impaired Elderly African American Volunteers: A Pilot Study</p>
Author(s) -
Thomas V. Fungwe,
Julius S. Ngwa,
Oyonumo Ntekim,
Joanne Allard,
Sheeba Nadarajah,
Saba Wolday,
Oludolapo Ogunlana,
Steven P. Johnson,
Kakra Hughes,
Daniel Larbi,
Richard F. Gillum,
Thomas O. Obisesan
Publication year - 2019
Publication title -
clinical interventions in aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 76
eISSN - 1178-1998
pISSN - 1176-9092
DOI - 10.2147/cia.s195878
Subject(s) - cardiorespiratory fitness , medicine , aerobic exercise , endocrinology , lipoprotein , triglyceride , lipoprotein particle , vo2 max , dyslipidemia , cholesterol , blood pressure , very low density lipoprotein , diabetes mellitus , heart rate
Poor cardiorespiratory fitness (CRF) is linked to cognitive deterioration, but its effects on lipid heterogeneity and functional properties in older African American (AA) subjects with mild cognitive impairment (MCI) need elucidation. This study determined whether exercise training-induced changes in blood lipid particle sizes (LPS) were associated with CRF determined by VO 2 Max in elderly AAs with MCI. Given the pivotal role of brain-derived neurotrophic factor (BDNF) on glucose metabolism, and therefore, "diabetic dyslipidemia", we also determined whether changes in LPS were associated with the levels of serum BDNF.