Peri‐operative systemic inflammation and intractable shock in a patient with Ewing's sarcoma

Summary Ewing's sarcoma is the second most frequently occurring primary bone malignancy, with a preponderance in children, adolescents and young adults. Overall five‐year survival is 60%. Treatment includes chemotherapy, surgical resection, limb salvage or amputation, and radiotherapy. Surgical complications most often result from haemorrhage or infection. We present a case of profound peri‐operative systemic inflammation and intractable shock that occurred during femoral diaphyseal replacement in a 41‐year‐old male. This phenomenon is previously unreported and serves as a cautionary note to anaesthetists.