Open AccessMastocytosis: anaphylaxis following emergency anaesthesia
Author(s) -
Baker Roisin,
McAlindon Michael,
Pierson Richard
Publication year - 2015
Publication title -
anaesthesia cases
Language(s) - English
Resource type - Journals
ISSN - 2396-8397
DOI - 10.21466/ac.mafea2.2015
Subject(s) - anaphylaxis , medicine , compromise , anesthesia , histamine , systemic mastocytosis , emergency surgery , general anaesthesia , intensive care medicine , allergy , surgery , mast cell , immunology , social science , sociology
Summary General anaesthesia in patients with known mastocytosis can be extremely hazardous. Massive histamine release may be triggered by drugs or by the psychological and environmental stresses associated with surgery and can result in significant cardiovascular collapse, respiratory compromise and even death. We present a case of anaphylaxis following induction of anaesthesia in a patient whose diagnosis of mastocytosis was not disclosed during pre‐assessment for emergency surgery. We believe it is the only case reported where the patient has survived their hospital admission in such circumstances despite significant and prolonged cardiovascular compromise.