Open AccessDelayed Onset Peripheral Nerve Blockade in a Patient with Congenital Myopathy
Author(s) -
Moosajee Vazira,
Egeler Christian,
Walters Richard Jon,
Topliss Claire,
Ford Simon
Publication year - 2014
Publication title -
anaesthesia cases
Language(s) - English
Resource type - Journals
ISSN - 2396-8397
DOI - 10.21466/ac.dopnbia.2014
Subject(s) - medicine , blockade , myopathy , connective tissue , neuromuscular blockade , anesthesia , pathology , receptor
Summary Reports of delayed induction or “all or nothing” local anaesthetic resistance are well documented in patients with connective tissue disorders [1] but, as yet, no clear relationship between myopathies and local anaesthetic resistance is known. We discuss a case of a five‐hour delay in onset of sciatic nerve blockade, on two separate occasions, in a patient with myosin storage myopathy, a form of congenital myopathy. We believe this to be first clinical documentation of such a phenomenon.