An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2 | Zendy

Pellegrino Cerino | Zendy; Annachiara Coppola | Zendy; Biancamaria Pierri | Zendy; Palmiero Volzone | Zendy; Dario Bruzzese | Zendy; Andrea Pierri | Zendy; Amedeo Ferro | Zendy; Daniela Schiavi | Zendy; Antonio Coppola | Zendy; Stefano Miniero | Zendy; Luigi Atripaldi | Zendy; Caterina Pirozzi | Zendy; Pasquale Rusciano | Zendy; Alessandra Macri | Zendy; Rita Boenzi | Zendy; Silvia Sale | Zendy; Gianfranco Brambilla | Zendy; Carlo Buonerba | Zendy

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An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2

Author(s) -

Pellegrino Cerino,

Annachiara Coppola,

Biancamaria Pierri,

Palmiero Volzone,

Dario Bruzzese,

Andrea Pierri,

Amedeo Ferro,

Daniela Schiavi,

Antonio Coppola,

Stefano Miniero,

Luigi Atripaldi,

Caterina Pirozzi,

Pasquale Rusciano,

Alessandra Macri,

Rita Boenzi,

Silvia Sale,

Gianfranco Brambilla,

Carlo Buonerba

Publication year - 2021

Publication title -

future science oa

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 23

ISSN - 2056-5623

DOI - 10.2144/fsoa-2021-0064

Subject(s) - medicine , adverse effect , incidence (geometry) , retrospective cohort study , thrombosis , cohort , aspirin , observational study , cohort study , optics , physics

In this retrospective study, a cohort of 67 subjects vaccinated with AZD1222 was retrospectively observed. Consistently with published findings, no serious adverse event was reported, and all adverse events reported (fever, muscle ache and/or pain in the site of injection) had resolved by day 8. Of note, some citizens were prescribed low-dose aspirin and even heparin for thrombosis prevention. We also found variations in laboratory test results (full blood count and chemistry) on day 1 compared with day 8. Physicians should be aware that no prevention therapy for thrombosis is currently recommended, given the very low incidence of this side effect. Additional studies are warranted to interpret our findings.

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