Open AccessSuccessful treatment with yttrium-90 microspheres in a metastatic breast cancer patient and sclerosing cholangitis
Author(s) -
Aurélie Louvet,
Cédric Van Marcke,
P. Dabadie,
Emmanuel Seront
Publication year - 2021
Publication title -
future science oa
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 23
ISSN - 2056-5623
DOI - 10.2144/fsoa-2021-0015
Subject(s) - medicine , malignancy , breast cancer , colorectal cancer , metastatic breast cancer , cancer , metastasis , radiation therapy , oncology
Breast cancer is the most common malignancy occurring in women worldwide. More than 90% of patients present with localized disease are treated with curative intent; however, recurrence can occur with development of metastatic lesions. Frequently associated with extra-hepatic lesions, localized treatments (surgery or stereotaxic body radiotherapy) are rarely proposed in liver lesions. 90 Y radioembolization has extensively been evaluated in colorectal cancer, but its role in breast cancer with isolated liver metastases remains largely unknown. Pre-existing liver diseases are known risk factors for 90 Y induced liver toxicity. Not considered as an excluding factor for this treatment, data are limited regarding its safe use with cholangitis. We report a successful control of liver metastases by 90 Y radioembolization in a breast cancer patient.