Open AccessVitamin and mineral supplementation for β-thalassemia during COVID-19 pandemic
Author(s) -
Annette d’Arqom,
Melvanda Gisela Putri,
Yovani Savitri,
Andi Muh Rahul Alfaidin
Publication year - 2020
Publication title -
future science oa
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 23
ISSN - 2056-5623
DOI - 10.2144/fsoa-2020-0110
Subject(s) - thalassemia , micronutrient , immune system , oxidative stress , pandemic , medicine , covid-19 , disease , physiology , immunology , infectious disease (medical specialty) , pathology
Aim: Low levels of immune-related micronutrients have been identified in β-thalassemia samples. Moreover, the excess amount of iron, contributing to oxidative stress in the pathogenesis of the disease, alters the immune system in β-thalassemia, which is important during the COVID-19 pandemic. Materials & Methods: Searches of PUBMED and EMBASE were conducted to identify the level and supplementation of micronutrients in β-thalassemia, published from 2001–May 2020. Results: The review found six observational and five interventional studies supporting the importance of supplementing vitamins and minerals among patients with β-thalassemia. Conclusion: Supplementation of immune-related vitamins and minerals might bring benefits to the immune system, especially in reducing oxidative stress in β-thalassemia.