Vitamin and Mineral Supplementation for β-Thalassemia During COVID-19 Pandemic | Zendy

Annette d’Arqom | Zendy; Melvanda Gisela Putri | Zendy; Yovani Savitri | Zendy; Andi Muh Rahul Alfaidin | Zendy

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Vitamin and Mineral Supplementation for β-Thalassemia During COVID-19 Pandemic

Author(s) -

Annette d’Arqom,

Melvanda Gisela Putri,

Yovani Savitri,

Andi Muh Rahul Alfaidin

Publication year - 2020

Publication title -

future science oa

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 23

ISSN - 2056-5623

DOI - 10.2144/fsoa-2020-0110

Subject(s) - thalassemia , micronutrient , immune system , oxidative stress , pandemic , medicine , covid-19 , disease , physiology , immunology , infectious disease (medical specialty) , pathology

Aim: Low levels of immune-related micronutrients have been identified in β-thalassemia samples. Moreover, the excess amount of iron, contributing to oxidative stress in the pathogenesis of the disease, alters the immune system in β-thalassemia, which is important during the COVID-19 pandemic. Materials & Methods: Searches of PUBMED and EMBASE were conducted to identify the level and supplementation of micronutrients in β-thalassemia, published from 2001–May 2020. Results: The review found six observational and five interventional studies supporting the importance of supplementing vitamins and minerals among patients with β-thalassemia. Conclusion: Supplementation of immune-related vitamins and minerals might bring benefits to the immune system, especially in reducing oxidative stress in β-thalassemia.

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