Open AccessLiquid biopsy in cancer using the Z-scan technique: a new approach to discover biomarkers in cancer
Author(s) -
Fernando Luiz Affonso Fonseca,
Gláucia Luciano da Veiga,
Beatriz da Costa Aguiar Alves,
Sarah Alves
Publication year - 2021
Publication title -
future science oa
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 23
ISSN - 2056-5623
DOI - 10.2144/fsoa-2020-0054
Subject(s) - liquid biopsy , cancer , medicine , cancer biomarkers , biopsy , solid tumor , oncology , medical physics , pathology
Aim: Biomarkers have been broadly studied as a tool for the diagnosis and prognosis for different types of cancer. Z-scan is a kind of measurement technique that generates a nonlinear refractive index (n 2 ). Today, Z-scan has been used in oncology to discriminate between solid tumors and to identify tumor circulating cell-free DNA in liquid samples. Materials & methods: According to the inclusion and exclusion criteria defined in this review, 35 articles were selected. Conclusion: The use of this technique for this kind of measurement will allow for a rapid and precise diagnosis of different types of tumor and may lead to better therapeutic approaches.