
Managing growing teratoma syndrome: new insights and clinical applications
Author(s) -
Srdjan Saso,
Nicolas Galazis,
Christos Iacovou,
Kleio Kappatou,
Menelaos Tzafetas,
Benjamin P Jones,
Joseph Yazbek,
Konstantinos Lathouras,
Jonathan Anderson,
Long R. Jiao,
Richard J. Smith
Publication year - 2019
Publication title -
future science oa
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 23
ISSN - 2056-5623
DOI - 10.2144/fsoa-2019-0075
Subject(s) - medicine , multidisciplinary team , germ cell tumors , general surgery , ovarian cancer , ovarian teratoma , teratoma , chemotherapy , cancer , surgery , intensive care medicine , nursing
Although a recognized condition, growing teratoma syndrome (GTS) has no guidelines for management, and patients diagnosed with the condition are managed empirically by the most appropriate teams. We report a case of GTS in a 33-year-old patient who was initially treated with unilateral salpingo-oophorectomy and subsequent chemotherapy for a germ cell ovarian tumor. GTS was subsequently diagnosed with massive pelvic and upper abdominal masses as well as lung tumors. We also conducted a literature review on cases of GTS presenting with large tumors. Based on this, we suggest a management plan to guide the care of women with GTS. The condition is best managed in a multidisciplinary team involving the relevant surgeons, including gynecologist, abdominal and thoracic surgeons.