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18F[AlF]-radiolabelled Peptides on the Automated Synthesis Platform: Translating the Laboratory Bench Work to Bedside
Author(s) -
Hishar Hassan,
Hairil Rashmizal Abdul Razak,
Fathinul Fikri Ahmad Saad,
Vijay Kumar
Publication year - 2019
Publication title -
the malaysian journal of medical sciences/the malaysian journal of medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.394
H-Index - 25
eISSN - 2180-4303
pISSN - 1394-195X
DOI - 10.21315/mjms2019.26.4.14
Subject(s) - bench to bedside , molecular imaging , in vivo , computational biology , chemistry , pet imaging , medicine , positron emission tomography , medical physics , nuclear medicine , biology , microbiology and biotechnology
Using radiolabelled peptides that bind, with high affinity and specificity, to receptors on tumour cells is one of the most promising fields in modern molecular imaging and targeted radionuclide therapy (1). In the emergence of molecular imaging and nuclear medicine diagnosis and therapy, albeit theranostic, radiolabelled peptides have become vital tools for in vivo visualisation and monitoring physiological and biochemical processes on molecular and cellular levels (2). This approach may benefit patients in the era of personalised medicine.

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