Open AccessTongue Ulcer as a Manifestation of Secondary HIV-Associated Multidrug-Resistant Tuberculosis
Author(s) -
А. В. Кукурика,
I. A. Iurovskaia,
E. I. Iurovskaia
Publication year - 2022
Publication title -
tuberkulez i bolezni lëgkih/tuberkulëz i bolezni lëgkih
Language(s) - English
Resource type - Journals
eISSN - 2542-1506
pISSN - 2075-1230
DOI - 10.21292/2075-1230-2022-100-2-48-52
Subject(s) - medicine , tuberculosis , differential diagnosis , tongue , mycobacterium tuberculosis , human immunodeficiency virus (hiv) , regimen , dermatology , multiple drug resistance , glossitis , drug resistance , extrapulmonary tuberculosis , medical prescription , pathology , immunology , microbiology and biotechnology , pharmacology , biology
Tuberculosis of the tongue is one of the rare localizations of extrapulmonary tuberculosis. The article presents a clinical case of secondary tuberculous glossitis with concurrent multidrug-resistant pulmonary tuberculosis in a 35-year-old HIV-infected patient. Despite relatively rapid verification of the diagnosis, the clinical situation was difficult due to differential diagnosis with nonspecific lesions, unknown HIV status, and detection of drug resistance of Mycobacterium tuberculosis. This case illustrates the step-by-step diagnosis and treatment of tuberculous ulcers of the tongue and lungs. The comprehensive examination with the use of molecular genetic, bacteriological, histological, and X-ray diagnostic tools contributed to the timely prescription of the adequate anti-tuberculosis therapy regimen.