Open AccessContemporary approaches to the search for active drugs and chemotherapy regimens for tuberculosis treatment
Author(s) -
T.K. Lugovkina,
Sergey Skornyakov,
Elena Kildyusheva,
Eugene Egorov
Publication year - 2020
Publication title -
tuberkulez i bolezni lëgkih/tuberkulëz i bolezni lëgkih
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.226
H-Index - 12
eISSN - 2542-1506
pISSN - 2075-1230
DOI - 10.21292/2075-1230-2020-98-6-60-69
Subject(s) - tuberculosis , antimicrobial , antimicrobial chemotherapy , medicine , chemotherapy , drug , intensive care medicine , clinical trial , pharmacology , mycobacterium tuberculosis , oncology , biology , pathology , microbiology and biotechnology
The article analyzes scientific publications (37 articles) devoted to phthisiology, clinical pharmacology of antimicrobial agents, laboratory methods for evaluating the effectiveness and safety of various regimens of tuberculosis chemotherapy caused by resistant strains of M. tuberculosis . It tells about prospects for expanding the line of antimicrobial agents for treatment of tuberculosis caused by resistant strains of M. tuberculosis , new approaches to the study and evaluation of the effectiveness of the drug at the stage of preclinical trials using the in vitro HFS-TV model.