Open AccessIMPACT OF BEDAQUILINE ON THE EFFICIENCY OF COMPREHENSIVE THERAPY OF RESPIRATORY TUBERCULOSIS
Author(s) -
Mari. Kondakova,
В. В. Хабиров,
В. Ф. Жемков,
Л. Р. Шпаковская,
А. В. Дайновец,
А. В. Елькин
Publication year - 2018
Publication title -
tuberkulez i bolezni lëgkih/tuberkulëz i bolezni lëgkih
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.226
H-Index - 12
eISSN - 2542-1506
pISSN - 2075-1230
DOI - 10.21292/2075-1230-2018-96-6-39-43
Subject(s) - medicine , bedaquiline , tuberculosis , dispensary , regimen , respiratory system , surgery , pathology , mycobacterium tuberculosis
The objective of the study: to evaluate the possibility to enhance the clinical efficiency of treatment of pulmonary tuberculosis patients by adding bedaquiline to the fifth chemotherapy regimen. Subjects and methods . The presented results were obtained through dynamic follow-up and treatment of 68 respiratory tuberculosis patients, treated in St. Petersburg TB Dispensary from 2014 to 2016. Results . The clinical improvement manifested through relief of intoxication symptoms, normalization of blood count, reduction of infiltrate changes and healing of destruction. In a number of cases, relief of intoxication symptoms with reduction of bacillary excretion massiveness, infiltration and cavity sizes allowed preparing patients for the next stage of treatment – surgery.