Open AccessMAGNETIC NANOLIPOSOMES: A REVIEW ON PREPARATION AND CHARACTERIZATION METHODS
Author(s) -
P. Selvamani,
Venkata Krishnan Par,
Rosi Rajamanickam,
Latha Subbiah
Publication year - 2021
Publication title -
bulletin of pharmaceutical research
Language(s) - English
Resource type - Journals
eISSN - 2249-9245
pISSN - 2249-6041
DOI - 10.21276/bpr.2021.11.3
Subject(s) - nanocarriers , materials science , magnetic nanoparticles , liposome , ferrofluid , sonication , nanoparticle , microemulsion , nanotechnology , drug delivery , characterization (materials science) , dispersity , extrusion , chemical engineering , chromatography , pulmonary surfactant , chemistry , magnetic field , polymer chemistry , engineering , metallurgy , physics , quantum mechanics
Magnetic nanoliposomes are versatile nanocarriers for targeted drug delivery. These liposomes can enhance the efficacy of bioactive compounds by improving pharmacokinetic parameters. Chemical ingredients of magnetic nanoliposomes include ferrofluid, cholesterol and phospholipid molecules. The preparation of magnetic nanoliposomes involves two steps viz. synthesis of magnetic nanoparticles and then combination with prepared nanoliposomes. The magnetic nanoliposomes are synthesized by various chemical methods including co-precipitation, thermal decomposition, microemulsion and hydrothermal synthesis. The nanoliposomes are prepared by sonication, extrusion, micro-fluidization techniques. Characterization studies included size, nanoparticle tracking analysis, flow cytometry, size exclusion chromatography, DSC, encapsulation efficiency. This study provides an overview of the preparation and characterization techniques of magnetic nanoliposomes.