Open AccessLobular Endocervical Glandular Hyperplasia: A case report
Author(s) -
Kunjal Lila,
Roshani Hansraj Gala
Publication year - 2022
Publication title -
annals of pathology and laboratory medicine
Language(s) - English
Resource type - Journals
eISSN - 2394-6466
pISSN - 2349-6983
DOI - 10.21276/apalm.3102
Subject(s) - medicine , pathology , adenocarcinoma , immunohistochemistry , hyperplasia , cancer
Most cervical adenocarcinomas currently are HPV related. With increasing use of HPV vaccine, the prevalence of HPV related carcinomas may reduce & there might be relative increase in occurrence of non HPV related carcinomas. Gastric variant of cervical adenocarcinoma is one such HPV-independent carcinoma and recognized as distinct entity by WHO 2014. A spectrum of benign, premalignant and malignant endocervical lesions showing gastric differentiation have emerged in the past decade. Lobular endocervical glandular hyperplasia(LEGH) is one such benign precursor of gastric variant of cervical adenocarcinoma. We in this case report discuss various gross, histomorphologic, histochemical and immunohistochemical features of LEGH.