Open AccessLeptomeningeal Metastasis from Carcinoma Breast: A Case of Unknown to Known
Author(s) -
Princy S Soman,
A Hemalatha,
R Kalyani,
V Lakshmaiah
Publication year - 2021
Publication title -
annals of pathology and laboratory medicine
Language(s) - English
Resource type - Journals
eISSN - 2394-6466
pISSN - 2349-6983
DOI - 10.21276/apalm.3022
Subject(s) - medicine , presentation (obstetrics) , magnetic resonance imaging , breast carcinoma , metastasis , cerebrospinal fluid , brain metastasis , radiology , incidence (geometry) , carcinoma , pathology , breast cancer , cancer , physics , optics
Leptomeningeal metastasis is known to occur as an initial presentation in solid tumors. The presentation of meningeal symptoms before the diagnosis of primary tumor is seen in 10-20% cases. Though the sophisticated radiological imaging is available, Cerebrospinal Fluid (CSF) analysis for tumor cells remains the gold standard method for diagnosis. Incidence of brain metastasis from primary carcinoma breast is about 3-8% only.
We present a case of young female who presented with neurological symptoms and misdiagnosed as meningitis on Magnetic Resonance Imaging (MRI), but later after CSF analysis it was diagnosed as metastases from carcinoma breast.