Open AccessCharacterization of pressure-driven water flows in nanofluidic channels by mass flowmetry
Author(s) -
Yutaka Kazoe,
Sho Kubori,
Kyojiro Morikawa,
Kazuma Mawatari,
Takehiko Kitamori
Publication year - 2022
Publication title -
analytical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.392
H-Index - 73
eISSN - 1348-2246
pISSN - 0910-6340
DOI - 10.2116/analsci.21p198
Subject(s) - nanofluidics , chemistry , volumetric flow rate , viscosity , analytical chemistry (journal) , flow (mathematics) , open channel flow , nanotechnology , mechanics , chromatography , composite material , materials science , physics
With developments in analytical devices promoted by nanofluidics, estimation of the flow rate in a nanochannel has become important to calculate volumes of samples and reagents in chemical processing. However, measurement of the flow rate in nanospaces remains challenging. In the present study, a mass flowmetry system was developed, and the flow rate of water by pressure-driven flow in a fused-silica nanochannel was successfully measured in picoliters per second. We revealed that the water flow rate is dependent on the viscosity significantly increased in a square nanochannel with 10 2 nm width and depth (3.6 times higher than the bulk viscosity for a representative channel size of 190 nm) and slightly increased in a plate nanochannel with micrometer-scale width and 10 2 nm depth (1.3 times higher for that of 234 nm), because of dominant surface effects. The developed method and results obtained will greatly contribute to nanofluidics and other related fields.