Open AccessEFEK PENGGUNAAN KETAMIN-XILAZIN DAN PROPOFOL TERHADAP DENYUT JANTUNG DAN PERNAFASAN PADA ANJING JANTAN LOKAL (Canis familiaris) (Effect of Ketamine-Xylazine and Propofol on Heart Rate and Breathing Frequency of Local Male Dog (Canis familiaris))
Author(s) -
Arman Sayuti,
Ria Maulizar,
Syafruddin Syafruddin,
Erwin Erwin,
Frengky Frengky,
Muttaqien Muttaqien,
Budianto Panjaitan,
Zuraidawati Zuraidawati
Publication year - 2016
Publication title -
jurnal medika veterinaria
Language(s) - English
Resource type - Journals
ISSN - 2503-1600
DOI - 10.21157/j.med.vet..v10i1.4034
Subject(s) - propofol , ketamine , xylazine , anesthesia , heart rate , medicine , respiratory rate , premedication , atropine , anesthetic , blood pressure
The purpose of this study was to determine the effect of using ketamine-xylazin and propofol on heart rate and breathing in local male dogs (Canis familiaris). Six male dogs with average body weight ±2-3 kg were divided into 2 treatment groups, each group was subcutaneously injected with of atropine sulfate at dose of 0.04 mg/kg as premedication prior to anesthetic administration. The first group (K1) was intravenously injected with anesthetic combination of ketamine-xylazine at dose of 5.5 mg/kg and 1 mg/kg, respectively. The second group (K2) was given propofol at dose of 6.6 mg/kg intravenously. The heart rate and breathing were directly calculated using stethoscope and stopwatch with 10 minutes interval. Data were analyzed statistically using analysis of variance (Anova) with split-splot design and if there is a difference between the two groups followed by least significant difference test (LSD). The administration of ketamine-xylazin (K I) significantly (P 0.05). It can be concluded that there is no difference effects of given ketamine-xylazin and propofol against heart rate on local male dogs. But there was difference effect of administration ketamine-xylazin and propofol on respiratory frequency on local male dogs.