Open AccessAlisol B 23-acetate-induced HepG2 hepatoma cell death through mTOR signaling-initiated G1 cell cycle arrest and apoptosis: A quantitative proteomic study
Author(s) -
Jianguo Xia,
Qiang Luo,
Shengbin Huang,
Fuquan Jiang,
Lin Wang,
Guanghui Wang,
Jingjing Xie,
Jie Liu,
Yang Xu
Publication year - 2019
Publication title -
chinese journal of cancer research/chinese journal of cancer research
Language(s) - English
Resource type - Journals
eISSN - 1993-0631
pISSN - 1000-9604
DOI - 10.21147/j.issn.1000-9604.2019.02.12
Subject(s) - stable isotope labeling by amino acids in cell culture , pi3k/akt/mtor pathway , cell cycle , apoptosis , cell cycle checkpoint , quantitative proteomics , microbiology and biotechnology , biology , rptor , proteomics , programmed cell death , ribosome biogenesis , cell growth , chemistry , signal transduction , biochemistry , ribosome , rna , gene
The present study aimed to investigate the molecular events in alisol B 23-acetate (ABA) cytotoxic activity against a liver cancer cell line.