Open AccessThe effect of aqueous extracts and isolation proteinous compound from clove buds on serumglucose, triglyceride , glutathione and malnodialdehyde levels in alloxan induced diabetic mice
Author(s) -
Baghdad Science Journal
Publication year - 2010
Publication title -
mağallaẗ baġdād li-l-ʿulūm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.167
H-Index - 6
eISSN - 2411-7986
pISSN - 2078-8665
DOI - 10.21123/bsj.7.1.554-563
Subject(s) - alloxan , triglyceride , chemistry , cholesterol , glutathione , kidney , diabetes mellitus , food science , biochemistry , endocrinology , biology , enzyme
This study was included preparing acold aqueous extract of clove buds The study also comprised the isolation and studying the proteinous compound,which was seperated using gel filtration technique and determined approximately molecular weight of this isolated compound(6799) dalton . The aim of the study demonstrate effects of the crude aqueous, non proteinous extract, proteinous precipitate and proteinous compound on serum glucose, total cholesterol, triglyceride and high density lipoprotein-cholesterol levels, also glutathione and malondialdehyde levels in liver and kidney tissues in diabetic mice-induced alloxan.Extracts were administerated interaperitioneally. The results were indicated that the crude aqueous, non proteinous extract, proteinous precipitate and proteinous compound which were caused asignificant decrease in serum glucose, total cholesterol, triglyceride levels and malondialdehyde level in liver and kidney tissues, while aproteinous precipitate don’t show asignificant decrease in serum cholesterol level but all extracts don’t show asignificant changes in serum high density lipoprotein-cholesterol level in alloxan induced diabetic mice, on other wise all extractsshowed asignificant increase in glutathione level in liver and kidney tissues except non proteinous extract and proteinous precipitate which were caused asignificant increase in glutathione level in liver tissue only.