Open AccessSynthesis of Some Mixed ligands Complexes of (2-hydroxy benzaldine)-4-amino Antipyrine and 1,10-phenanthroline and Studying their antibacterial activity
Author(s) -
Baghdad Science Journal
Publication year - 2017
Publication title -
mağallaẗ baġdād li-l-ʿulūm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.167
H-Index - 6
eISSN - 2411-7986
pISSN - 2078-8665
DOI - 10.21123/bsj.14.1.39-47
Subject(s) - chemistry , ligand (biochemistry) , phenanthroline , octahedral molecular geometry , octahedron , antibacterial activity , magnetic susceptibility , nuclear chemistry , atomic absorption spectroscopy , transition metal , absorption (acoustics) , metal , schiff base , square pyramidal molecular geometry , stereochemistry , crystallography , ion , bacteria , organic chemistry , materials science , biochemistry , receptor , biology , physics , quantum mechanics , composite material , genetics , catalysis
Complexes from the ligand (2-hydroxy benzaldine)-4-aminoantipyrine with some transition metal ions V(l?),Cr(lll),Fe(lll) and Co(ll) were prepared in the presence of the co-ligand 1,10-phenanthroline in alcoholic medium. These compounds were characterized by the available techniques: FT-IR ,UV-Visible ,magnetic susceptibility, Flame atomic absorption technique as well as elemental analysis and conductivity mesurments .From these spectral studies, a square pyramidal structure proposed for V(IV) complex and an octahedral geometry for Cr(III),Fe(III) and Co(II) complexes. The biological activity of the ligands and their complexes were evaluated by a gar plate diffusion technique against three human pathogenic bacterial strains: Pseudomonas aerogenuosa, E.schriachia coli. and Staphlococcus arureus. Some of the complexes were found to have a good antibacterial activity a gainst these pathogens.