Spectrophotometric determination of cefixime by charge transfer complex formation | Zendy

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Spectrophotometric determination of cefixime by charge transfer complex formation

Author(s) -

Baghdad Science Journal

Publication year - 2013

Publication title -

baghdad science journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.167

H-Index - 6

eISSN - 2411-7986

pISSN - 2078-8665

DOI - 10.21123/bsj.10.3.971-976

Subject(s) - cefixime , chloranil , chemistry , complex formation , analytical chemistry (journal) , chromatography , inorganic chemistry , organic chemistry , biochemistry , cephalosporin , antibiotics

Simple, sensitive and economical spectrophotometric methods have been developed for the determination of cefixime in pure form. This method is based on the reaction of cefixime as n-electron donor with chloranil to give highly colored complex in ethanol which is absorb maximally at 550 nm. Beer's law is obeyed in the concentration ranges 5-250 µg ml-1 with high apparent molar absorptivities of 1.52×103 L.mole-1. cm-1.

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