z-logo
open-access-imgOpen Access
Increased Thyroid Hormone Levels in Pesticide Sprayer at Agricultural Area
Author(s) -
Aditya Sukma Pawitra,
Khuliyah Candraning Diyanah,
Mohd Talib Latif,
Beni Hari Susanto,
Muhammad Farid Dimjati Lusno
Publication year - 2022
Publication title -
kesmas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.146
H-Index - 3
eISSN - 2460-0601
pISSN - 1907-7505
DOI - 10.21109/kesmas.v17i1.5487
Subject(s) - pesticide , hormone , triiodothyronine , thyroid , medicine , endocrine system , organophosphate , toxicology , thyroid stimulating hormone , endocrinology , biology , agronomy
Pesticides still used massively in the agricultural sector would cause many poisoning and serious health problems. Organophosphate pesticides have been identified as endocrine-disrupting chemicals. This study aimed to analyze the comparison of thyroid hormone levels between the sprayers chronically exposed to pesticides and the control respondents who had never been exposed to pesticides. This study was an analytical observational with a cross-sectional design. The total number of respondents was 150, 50 as sprayers and 100 as control respondents. The venous blood samples were examined using the Enzyme-Linked Immunosorbent Assay (ELISA). The findings significantly showed that the sprayer had a higher level of thyroid-stimulating hormone (TSH) (4.776 ± 1.1166), lower triiodothyronine (T3) (108.822 ± 18.810), and lower thyroxine (T4) (7.808 ± 1.067). Determinant factors among sprayers that significantly correlated to TSH levels was (age = 0.006; work duration = 0.000; PPE = 0.045; body position = 0.014; type of pesticides = 0.004), correlated with T3 levels was (age = 0.037; body position = 0.045), correlated with T4 levels was (age = 0.000; PPE = 0.045). It could be concluded that chronic organophosphate exposure would increase TSH and decrease T3 and T4.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here