Open AccessMajor Inflammatory Markers and Their Significance in Predicting Severity of COVID-19 Disease Pattern
Author(s) -
Abdullah I. Aedh,
Ali Hajri,
Abdulaziz Alshahrani,
M Adam,
Abubaker Dahab,
Asaad Ma. Babker,
Hatem Mohamed
Publication year - 2021
Publication title -
international journal of biomedicine
Language(s) - English
Resource type - Journals
eISSN - 2158-0529
pISSN - 2158-0510
DOI - 10.21103/article11(4)_oa13
Subject(s) - covid-19 , medicine , outbreak , disease , retrospective cohort study , neutrophil to lymphocyte ratio , pandemic , oxygen saturation , immunology , intensive care medicine , lymphocyte , pathology , infectious disease (medical specialty) , chemistry , organic chemistry , oxygen
The unanticipated outbreak of the COVID-19 pandemic has shocked the world in terms of both lives and livelihood. SARS-CoV-2 virus primarily affects the respiratory system, although other organ systems are also involved. Early diagnosis followed up by a retrospective analysis and tracking of a few markers relevant to the immunological status of the individual may aid in determining the state of the patient's disease prognosis. The aim of the present study was to evaluate immunological parameters such as neutrophil to lymphocyte ratio (NLR), C-reactive protein (CRP), and D-dimer, taking into account the patient's age and oxygen saturation level. Our retrospective analysis of clinical data revealed that such parameters as CRP, D-dimer, and NLR should be taken into consideration to predict severe COVID-19-related complications. The data obtained indicate that patients over age 60 are especially vulnerable to severe COVID-19.