Open AccessA New Perspective on a Morphological Confirmation of the Tissue Repair Process in the Experimental Simulation of a Surgical Dental Extraction in Rats
Author(s) -
A. B. Antonyan,
Д. И. Харитонов,
А. В. Подопригора,
I.K. Stepanov,
Оleg Shalaev,
И. А. Беленова,
Elena Lecsheva,
A. E. Petrosyan
Publication year - 2021
Publication title -
international journal of biomedicine
Language(s) - English
Resource type - Journals
eISSN - 2158-0529
pISSN - 2158-0510
DOI - 10.21103/article11(2)_oa8
Subject(s) - extraction (chemistry) , connective tissue , dentistry , medicine , process (computing) , mandibular incisor , fibrosis , incisor , surgery , pathology , chemistry , computer science , chromatography , operating system
All stages of a surgical dental extraction are accompanied by risks of various complications. Many ways and methods have been created in order to prevent the development of complications of different genesis. However, this issue still remains relevant since dental surgeons face the challenge of inflammation problems during the post-extraction period. The use of male Wistar rats as a model organism for a surgical extraction of a lower incisor allows us to conduct visual, histological and immunohistochemical evaluations of the wound healing process. The main objective of this study was to compare the effect of ionic silver solution and hydrogen water in high concentration when irrigating the operational field of a surgical dental extraction on the lower jaw. The results obtained showed that the use of water with an increased content of molecular hydrogen during the treatment is able to stimulate the recovery of the EM of the connective periodontal tissue to a greater extent than the ionic silver solution, connected to the participation of MCs and their secretome.