Open AccessEvaluation of Liver in Type 2 Diabetes Mellitus Using Unenhanced Computed Tomography
Author(s) -
Huda Osama,
Afraa Siddig,
Awadia Gareeballah,
Moawia Gameraddin,
Hanady Elyas Osman
Publication year - 2020
Publication title -
international journal of biomedicine
Language(s) - English
Resource type - Journals
eISSN - 2158-0529
pISSN - 2158-0510
DOI - 10.21103/article10(4)_oa14
Subject(s) - medicine , cirrhosis , diabetes mellitus , type 2 diabetes mellitus , pancreas , gastroenterology , fatty liver , computed tomography , etiology , chronic liver disease , liver disease , spleen , radiology , disease , endocrinology
Background: Chronic liver disease occurs due to different etiologies. Most diabetic patients are unaware that the effective control of hyperglycemia might reduce complications and mortality rates. Fatty liver disease is considered a risk factor of hepatic cirrhosis and cancers. Methods and Results: We conducted a case-control study to assess the impact of type 2 diabetes mellitus (T2DM) on the liver using a CT scan. A total of 100 patients with T2DM and 96 non-diabetic patients as a control group were selected using a convenient sampling method. There was a significant difference in liver attenuation in diabetic and control groups. The CT attenuation values of the liver, pancreas, and spleen were significantly lower in patients with T2DM than in non-diabetics (P<0.001). There was a significant negative correlation between the duration of T2DM and CT attenuation of the liver, pancreas, and spleen (P<0.01). Conclusion: The CT attenuation of the liver was significantly lower in T2DM than in the non-diabetic patients, and liver attenuation decreased as the duration of T2DM increased.