Open AccessMassive Proteinuria which Rapidly Resolved after Discontinuation of Regorafenib
Author(s) -
Mehmet Zahid Koçak,
Gülali Aktaş,
Satılmış Bilgin,
Tuba Taslamacıoğlu Duman,
Özge Kurtkulağı,
Burçin Meryem Atak Tel,
Irem Emir Ozcil,
Haluk Şavlı
Publication year - 2021
Publication title -
national journal of health sciences
Language(s) - English
Resource type - Journals
eISSN - 2519-7878
pISSN - 2519-7053
DOI - 10.21089/njhs.53.0136
Subject(s) - regorafenib , proteinuria , discontinuation , medicine , adverse effect , pediatrics , gastroenterology , kidney , colorectal cancer , cancer
Regorafenib is treatment option of cancers. It is associated with several adverse effects, including proteinuria. We report a massive proteinuria associated with regorafenib which resolved quickly after discontinuation of the drug. A 63 year old male presented with diarrhea and bilateral swallowing of legs. In urinanalysis, 18.5 g/day of proteinuria was detected. All symptoms, including proteinuria, resolved after discontinuation of regorafenib. Despite cessation of regorafenib treatment is advised in case of proteinuria, we suggest that regorafenib associated proteinuria could be rapidly resolved after discontinuation of the drug.