Open AccessOral Spindle Cell Carcinoma –Diagnosis Based on Immunohistochemical Interpretation
Author(s) -
Syeda Asiya Butool,
Ankit Natani,
Betina Chandolia,
Manas Bajpai
Publication year - 2021
Publication title -
national journal of health sciences
Language(s) - English
Resource type - Journals
eISSN - 2519-7878
pISSN - 2519-7053
DOI - 10.21089/njhs.53.0133
Subject(s) - immunohistochemistry , medicine , dysphagia , pathology , swallowing , spindle cell carcinoma , metastasis , lesion , tongue , basal cell , cell , cancer , biology , radiology , genetics
Spindle Cell Carcinoma (SpCC) is a biphasic tumor. They are proven to be monoclonal dedifferentiated forms of conventional squamous carcinomas. It is a rare tumor which is infrequently observed in head, neck and in the aerodigestive tract. The tumor is aggressive and shows high frequency of recurrence and metastasis. It is an aggressive variant of squamous cell carcinoma which resembles a true sarcoma. It is a proliferation of spindle cells and squamous cells. For confirmation of diagnosis, immunohistochemistry is used. A Rare case of spindle cell squamous cell carcinoma in a 61 years old male in the tongue.The patient reported of rapidly growing lesion from six months with pain severe pain, dysphagia and difficulty in swallowing patient had history of chewing tobacco from past 35 years. Keywords: Spindle Cell Variant, Biphasic tumor, Head and Neck, Pseudocarcinoma, Sqamous cell, Dysplastic.