Open AccessAlcohol Induced Liver Cirrhosis and its Treatment
Author(s) -
Mohit Gururan
Publication year - 2020
Publication title -
indian journal of medical and health sciences
Language(s) - English
Resource type - Journals
eISSN - 2455-4294
pISSN - 2347-9981
DOI - 10.21088/ijmhs.2347.9981.7220.8
Subject(s) - cirrhosis , alcoholic liver disease , medicine , pathological , liver injury , liver disease , alcohol , stomach , alcohol consumption , gastroenterology , fatty liver , liver cancer , cancer , disease , biology , biochemistry
The advent of liver diseases globally contributes to a major burden in terms of mortality rate and disease factor. The liver, which is a major complex organ, plays a vital role in the metabolism of the body. The diseases associated with the consumption of alcohol such as cirrhosis and cancer that can be diagnosed through various pathological and cytopathological methods. This review insights how the normally functioning liver cells become vulnerable and lead to the onset of various fatal disorders if left untreated. The alcohol, unlike other drinks, is directly absorbed from the stomach into the bloodstream and is further metabolized by the hepatocytes. The products of alcohol breakdown, such as aldehyde, are toxic to hepatocytes and thus cause liver injury, in cases of chronic alcohol consumption. This injury to the hepatocytes evolves over time and leads to liver cirrhosis. The only cure for severe liver cirrhosis is a transplant of the liver. On the whole, the widespread consumption of alcohol, its making, and effects on the hepatocytes on chronic consumption, which leads to alcoholic liver diseases reviewed.