Open AccessLiposomal and Suspension Forms of Immunoglobulins Against Ebola Fever as the New Medical Preparations
Author(s) -
Н. М. Зубавичене,
В. В. Золин,
E. A. Stavsky
Publication year - 2011
Publication title -
problemy osobo opasnyh infekcij
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.16
H-Index - 3
eISSN - 2658-719X
pISSN - 0370-1069
DOI - 10.21055/0370-1069-2011-4(110)-57-60
Subject(s) - antibody , liposome , incubation period , medicine , incubation , virology , immunology , chemistry , biochemistry
Presented are the results of investigation of therapeutic effectiveness of liposomal and suspension forms of immunoglobulins, prepared on the basis of 10 % goat immunoglobulin against Ebola fever. The most pronounced therapeutic and preventive effect on guinea pigs with experimental Ebola fever was achieved by double administration of suspended immunoglobulin against Ebola fever. The incubation period increased twofold, 37,5 % of infected animals survived. The results achieved are perspective for further development of new immunoglobulin preparations on the basis of liposomes and nanoemulsions.