Open AccessElaboration of the Algorithm of MLST-Typing of Pandemic and Pre-Pandemic <i>V. cholerae</i> El Tor strains
Author(s) -
A. V. Ossin,
Ya. M. Krasnov,
Natalya V. Guseva,
Н. И. Смирнова
Publication year - 2011
Publication title -
problemy osobo opasnyh infekcij
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.16
H-Index - 3
eISSN - 2658-719X
pISSN - 0370-1069
DOI - 10.21055/0370-1069-2011-1(107)-58-61
Subject(s) - vibrio cholerae , pandemic , housekeeping gene , multilocus sequence typing , typing , el tor , cholera , biology , virulence , virology , locus (genetics) , microbiology and biotechnology , gene , covid-19 , genetics , bacteria , medicine , infectious disease (medical specialty) , genotype , gene expression , disease , pathology
Molecular typing of pandemic and pre-pandemic cholera vibrio strains was carried out with the help of multi-locus sequence analysis. Application of two MLST schemes based on the sequence of virulence-associated and housekeeping genes demonstrated the last one to be the most effective in differentiation of strains, isolated before and during the seventh cholera pandemic.