Open AccessDevelopment of New Approaches of Obtaining the Hyperimmune Sera for Production of Medical Immunobiological Preparations
Author(s) -
Е. Н. Афанасьев,
И. С. Тюменцева,
О. И. Коготкова,
Л. В. Ляпустина,
И. В. Жарникова,
И. В. Савельева,
Д. А. Будыка
Publication year - 2010
Publication title -
problemy osobo opasnyh infekcij
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.16
H-Index - 3
eISSN - 2658-719X
pISSN - 0370-1069
DOI - 10.21055/0370-1069-2010-1(103)-67-69
Subject(s) - tularemia , immunization , immune system , immunology , antigen , leptospirosis , virology , plague (disease) , cholera , biology , microbiology and biotechnology , medicine , pathology
Developed were the new immunization schedules of obtaining plague, brucellar, anthrax, tularemia, cholera, leptospirosis, legionellosis and campilobacteriosis hyperimmune sera based on optimal combinations of specific protein antigenic complexes with immunomodulators, providing high specific immune response in 100 % of animals, significant reduction of immunization terms, material and labor input. Immune sera obtained are high quality biological material to be used for production of different diagnostic immunobiological preparations.